 Tiamutin is an antibiotic of the pleuromutilin family and is not related to other antibiotics, such
as the macrolides (tylosin,
kitasamycin, erythromycin, josamycin and spiramycin), or
the tetracyclines and there is no cross-resistance between the families. Due to its lack of cross-resistance Tiamutin has shown to be active against tylosin-resistant strains from Germany and Middle East. (Hinz, K.H. 1980, Levisohn, 1981)
No human use
Tiamutin is not used in human medicine so there is no fear
of cross-resistance with human antibiotics unlike the fluoroquinolones, macrolides, lincomycin or tetracyclines.
This statement has been confirmed publicly by the EU CVMP.
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