In an independent study [?] using 8 week old birds, Denagard was given at 0.0125% and 0.025% and tylosin at 0.05% in the drinking water over a 48 hour period. Denagard achieved 3 and 6 times higher serum levels respectively than tylosin even though it was given at 4 and 2 times the concentration. (See chart and table below).
| High blood levels |
| Denagard® (tiamulin) and tylosin levels in chicken serum (48 hours in drinking water; n=20) |
 |
| High blood levels |
| Comparative average rolling serum levels |
| Antibiotic |
Concentration |
Estimated drug intake
(mg/kg) |
Serum level over 48hrs
(µg/ml) |
| Denagard® (tiamulin) |
0.025% |
40 |
0.78 |
| Denagard® (tiamulin) |
0.0125% |
20 |
0.38 |
| Tylosin |
0.05% |
80 |
0.12 |
|
| 
